Role for acetylcholine in mediating effects of light on reproduction

David J. Earnest; Fred W. Turek

doi:10.1126/science.6849121

Role for acetylcholine in mediating effects of light on reproduction

David J. Earnest^*, Fred W. Turek

^*Corresponding author for this work

Neurobiology

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The length of day, or photoperiod, regulates the annual cycle of reproductive activity in the golden hamster. The inhibitory effects of a short-day photoperiod on testicular function were prevented by nighttime, but not daytime, intraventricular injections of carbachol, a cholinergic agonist. Short pulses of light during the night also block short-day induced testicular regression. The findings suggest that acetylcholine may play an important role in the mechanism through which information about the light-dark environment is transferred to the hypothalamic-pituitary-gonadal axis.

Original language	English (US)
Pages (from-to)	77-79
Number of pages	3
Journal	Science
Volume	219
Issue number	4580
DOIs	https://doi.org/10.1126/science.6849121
State	Published - 1983

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AU - Turek, Fred W.

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AB - The length of day, or photoperiod, regulates the annual cycle of reproductive activity in the golden hamster. The inhibitory effects of a short-day photoperiod on testicular function were prevented by nighttime, but not daytime, intraventricular injections of carbachol, a cholinergic agonist. Short pulses of light during the night also block short-day induced testicular regression. The findings suggest that acetylcholine may play an important role in the mechanism through which information about the light-dark environment is transferred to the hypothalamic-pituitary-gonadal axis.

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Role for acetylcholine in mediating effects of light on reproduction

Abstract

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