Role for acetylcholine in mediating effects of light on reproduction

David J. Earnest*, Fred W. Turek

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


The length of day, or photoperiod, regulates the annual cycle of reproductive activity in the golden hamster. The inhibitory effects of a short-day photoperiod on testicular function were prevented by nighttime, but not daytime, intraventricular injections of carbachol, a cholinergic agonist. Short pulses of light during the night also block short-day induced testicular regression. The findings suggest that acetylcholine may play an important role in the mechanism through which information about the light-dark environment is transferred to the hypothalamic-pituitary-gonadal axis.

Original languageEnglish (US)
Pages (from-to)77-79
Number of pages3
Issue number4580
StatePublished - 1983

ASJC Scopus subject areas

  • General


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