Role for the guanine nucleotide exchange factor phosphatidylinositol-3,4,5- trisphosphate-dependent rac exchanger 1 in platelet secretion and aggregation

Medicine and Dentistry

• Platelet 100%
• Agonist 83%
• G Protein Coupled Receptor 50%
• Thrombocyte Aggregation 50%
• Secretion (Process) 33%
• Low Drug Dose 33%
• Collagen 33%
• Thrombocyte Release Reaction 33%
• Phosphatidylinositol 3,4,5 Trisphosphate 33%
• Adenosine Triphosphate 16%
• Phosphorylation 16%
• Stimulation 16%
• Amino Terminal Sequence 16%
• Phosphotransferase 16%
• Thrombocyte Function 16%
• Bleeding Time 16%
• Phagocyte 16%
• Mitogen Activated Protein Kinase P38 16%
• Western Blot 16%
• Thrombin 16%
• 15 Hydroxy 11alpha,9alpha Epoxymethanoprosta 5,13 Dienoic Acid 16%
• Thrombocyte Activation 16%
• Guanine Nucleotide Exchange Factor 16%
• Absence 16%
• Neutrophil 16%

INIS

• secretion 66%
• aggregation 66%
• receptors 50%
• g-proteins 50%
• mice 33%
• kinases 33%
• collagen 33%
• doses 33%
• humans 16%
• proteins 16%
• comparative evaluations 16%
• stimulation 16%
• defects 16%
• nucleotides 16%
• phosphorylation 16%
• concentration 16%
• increasing 16%
• atp 16%
• neutrophils 16%
• mitogens 16%
• guanine 16%
• phagocytes 16%
• thrombin 16%
• phosphorus 38 16%