Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

I. Yu Rauschenbach*, M. Jh Sukhanova, L. V. Shumnaya, N. E. Gruntenko, L. G. Grenback, T. M. Khlebodarova, N. A. Chentsova

*Corresponding author for this work

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.

Original languageEnglish (US)
Pages (from-to)729-734
Number of pages6
JournalInsect Biochemistry and Molecular Biology
Volume27
Issue number8-9
DOIs
StatePublished - Aug 1 1997
Externally publishedYes

Keywords

  • DOPA decarboxylase
  • Dopamine
  • Drosophila virilis
  • Heat stress
  • N-acetyl transferase

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Insect Science

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