Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

I. Yu Rauschenbach; M. Jh Sukhanova; L. V. Shumnaya; N. E. Gruntenko; L. G. Grenback; T. M. Khlebodarova; N. A. Chentsova

doi:10.1016/S0965-1748(97)00051-9

Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

I. Yu Rauschenbach^*, M. Jh Sukhanova, L. V. Shumnaya, N. E. Gruntenko, L. G. Grenback, T. M. Khlebodarova, N. A. Chentsova

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.

Original language	English (US)
Pages (from-to)	729-734
Number of pages	6
Journal	Insect Biochemistry and Molecular Biology
Volume	27
Issue number	8-9
DOIs	https://doi.org/10.1016/S0965-1748(97)00051-9
State	Published - Aug 1997
Externally published	Yes

Funding

Research described in this publication was supported by grant RAROOO from the International Science Foundation, by a grant from the Russian State Scientific Programme `Priority Directions in Genetics', and by a grant from the Russian Fundamental Research Foundation. Gratitude is expressed to N. Chentsova for translating this paper from Russian into English.

Keywords

DOPA decarboxylase
Dopamine
Drosophila virilis
Heat stress
N-acetyl transferase

ASJC Scopus subject areas

Insect Science
Molecular Biology
Biochemistry

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10.1016/S0965-1748(97)00051-9

Cite this

Rauschenbach, I. Y., Sukhanova, M. J., Shumnaya, L. V., Gruntenko, N. E., Grenback, L. G., Khlebodarova, T. M., & Chentsova, N. A. (1997). Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions. Insect Biochemistry and Molecular Biology, 27(8-9), 729-734. https://doi.org/10.1016/S0965-1748(97)00051-9

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title = "Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions",

abstract = "Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.",

keywords = "DOPA decarboxylase, Dopamine, Drosophila virilis, Heat stress, N-acetyl transferase",

author = "Rauschenbach, {I. Yu} and Sukhanova, {M. Jh} and Shumnaya, {L. V.} and Gruntenko, {N. E.} and Grenback, {L. G.} and Khlebodarova, {T. M.} and Chentsova, {N. A.}",

note = "Funding Information: Research described in this publication was supported by grant RAROOO from the International Science Foundation, by a grant from the Russian State Scientific Programme `Priority Directions in Genetics', and by a grant from the Russian Fundamental Research Foundation. Gratitude is expressed to N. Chentsova for translating this paper from Russian into English. ",

year = "1997",

month = aug,

doi = "10.1016/S0965-1748(97)00051-9",

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Rauschenbach, IY, Sukhanova, MJ, Shumnaya, LV, Gruntenko, NE, Grenback, LG, Khlebodarova, TM & Chentsova, NA 1997, 'Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions', Insect Biochemistry and Molecular Biology, vol. 27, no. 8-9, pp. 729-734. https://doi.org/10.1016/S0965-1748(97)00051-9

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T1 - Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

AU - Rauschenbach, I. Yu

AU - Sukhanova, M. Jh

AU - Shumnaya, L. V.

AU - Gruntenko, N. E.

AU - Grenback, L. G.

AU - Khlebodarova, T. M.

AU - Chentsova, N. A.

N1 - Funding Information: Research described in this publication was supported by grant RAROOO from the International Science Foundation, by a grant from the Russian State Scientific Programme `Priority Directions in Genetics', and by a grant from the Russian Fundamental Research Foundation. Gratitude is expressed to N. Chentsova for translating this paper from Russian into English.

PY - 1997/8

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N2 - Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.

AB - Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.

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KW - Heat stress

KW - N-acetyl transferase

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Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

Abstract

Funding

Keywords

ASJC Scopus subject areas

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