Role of lower esophageal sphincter incompetence in recurrent pneumonia after repair of esophageal atresia

Peter F. Whitington; Dennis W. Shermeta; Dexter S Y Seto; Linda Jones; Thomas R. Hendrix

doi:10.1016/S0022-3476(77)80500-3

Role of lower esophageal sphincter incompetence in recurrent pneumonia after repair of esophageal atresia

Peter F. Whitington^*, Dennis W. Shermeta, Dexter S Y Seto, Linda Jones, Thomas R. Hendrix

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

The etiology of recurrent aspiration pneumonitis after the successful repair of esophageal atresia has not been defined. In order to explain this occurrence, we performed esophageal manometric examinations on eight patients who had undergone repair of EA and tracheoesophageal fistula. Two patients who had had recurrent pneumonia had subnormal pressure of the lower esophageal sphincter; they also had a history of severe regurgitation, and a barium esophagram demonstrated free gastroesophageal reflux. The LES incompetence in these patients was apparently corrected by administration of bethanechol.

Original language	English (US)
Pages (from-to)	550-554
Number of pages	5
Journal	The Journal of pediatrics
Volume	91
Issue number	4
DOIs	https://doi.org/10.1016/S0022-3476(77)80500-3
State	Published - Oct 1977

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(77)80500-3

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title = "Role of lower esophageal sphincter incompetence in recurrent pneumonia after repair of esophageal atresia",

abstract = "The etiology of recurrent aspiration pneumonitis after the successful repair of esophageal atresia has not been defined. In order to explain this occurrence, we performed esophageal manometric examinations on eight patients who had undergone repair of EA and tracheoesophageal fistula. Two patients who had had recurrent pneumonia had subnormal pressure of the lower esophageal sphincter; they also had a history of severe regurgitation, and a barium esophagram demonstrated free gastroesophageal reflux. The LES incompetence in these patients was apparently corrected by administration of bethanechol.",

author = "Whitington, {Peter F.} and Shermeta, {Dennis W.} and Seto, {Dexter S Y} and Linda Jones and Hendrix, {Thomas R.}",

note = "Funding Information: From the Division of Gastroenterology, Departments of Pediatrics and Medicine and the Division of Pediatric Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205. Study supported by a grant (RR-52) from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health. *Reprint address: Department of Pediatrics, University of Wisconsin School of Medicine, Madison, W1 53706.",

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AU - Whitington, Peter F.

AU - Shermeta, Dennis W.

AU - Seto, Dexter S Y

AU - Jones, Linda

AU - Hendrix, Thomas R.

N1 - Funding Information: From the Division of Gastroenterology, Departments of Pediatrics and Medicine and the Division of Pediatric Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205. Study supported by a grant (RR-52) from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health. *Reprint address: Department of Pediatrics, University of Wisconsin School of Medicine, Madison, W1 53706.

PY - 1977/10

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N2 - The etiology of recurrent aspiration pneumonitis after the successful repair of esophageal atresia has not been defined. In order to explain this occurrence, we performed esophageal manometric examinations on eight patients who had undergone repair of EA and tracheoesophageal fistula. Two patients who had had recurrent pneumonia had subnormal pressure of the lower esophageal sphincter; they also had a history of severe regurgitation, and a barium esophagram demonstrated free gastroesophageal reflux. The LES incompetence in these patients was apparently corrected by administration of bethanechol.

AB - The etiology of recurrent aspiration pneumonitis after the successful repair of esophageal atresia has not been defined. In order to explain this occurrence, we performed esophageal manometric examinations on eight patients who had undergone repair of EA and tracheoesophageal fistula. Two patients who had had recurrent pneumonia had subnormal pressure of the lower esophageal sphincter; they also had a history of severe regurgitation, and a barium esophagram demonstrated free gastroesophageal reflux. The LES incompetence in these patients was apparently corrected by administration of bethanechol.

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Role of lower esophageal sphincter incompetence in recurrent pneumonia after repair of esophageal atresia

Abstract

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