Rol de los microARN en las enfermedades pulmonares

Martín Angulo; Emilia Lecuona; Jacob Iasha Sznajder

doi:10.1016/j.arbr.2012.06.015

Rol de los microARN en las enfermedades pulmonares

Translated title of the contribution: Role of MicroRNAs in Lung Disease

Martín Angulo, Emilia Lecuona, Jacob Iasha Sznajder^*

^*Corresponding author for this work

Medicine, Pulmonary Division

Research output: Contribution to journal › Short survey › peer-review

67 Scopus citations

Abstract

MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

Translated title of the contribution	Role of MicroRNAs in Lung Disease
Original language	Spanish
Pages (from-to)	325-330
Number of pages	6
Journal	Archivos de Bronconeumologia
Volume	48
Issue number	9
DOIs	https://doi.org/10.1016/j.arbr.2012.06.015
State	Published - Sep 2012

Keywords

Asthma
Chronic obstructive pulmonary disease
Lung cancer
Lung disease
Lung injury
MicroRNA
Pulmonary fibrosis
Smoking

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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title = "Rol de los microARN en las enfermedades pulmonares",

abstract = "MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.",

keywords = "Asthma, Chronic obstructive pulmonary disease, Lung cancer, Lung disease, Lung injury, MicroRNA, Pulmonary fibrosis, Smoking",

author = "Mart{\'i}n Angulo and Emilia Lecuona and Sznajder, {Jacob Iasha}",

year = "2012",

month = sep,

doi = "10.1016/j.arbr.2012.06.015",

language = "Spanish",

volume = "48",

pages = "325--330",

journal = "Archivos de Bronconeumologia",

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T1 - Rol de los microARN en las enfermedades pulmonares

AU - Angulo, Martín

AU - Lecuona, Emilia

AU - Sznajder, Jacob Iasha

PY - 2012/9

Y1 - 2012/9

N2 - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

AB - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

KW - Asthma

KW - Chronic obstructive pulmonary disease

KW - Lung cancer

KW - Lung disease

KW - Lung injury

KW - MicroRNA

KW - Pulmonary fibrosis

KW - Smoking

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U2 - 10.1016/j.arbr.2012.06.015

DO - 10.1016/j.arbr.2012.06.015

M3 - Short survey

C2 - 22607962

AN - SCOPUS:84864832116

VL - 48

SP - 325

EP - 330

JO - Archivos de Bronconeumologia

JF - Archivos de Bronconeumologia

SN - 0300-2896

IS - 9

ER -

Rol de los microARN en las enfermedades pulmonares

Abstract

Keywords

ASJC Scopus subject areas

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