Abstract
MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.
| Original language | Spanish |
|---|---|
| Pages (from-to) | 325-330 |
| Number of pages | 6 |
| Journal | Archivos de Bronconeumologia |
| Volume | 48 |
| Issue number | 9 |
| DOIs | |
| State | Published - Jan 1 2012 |
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Keywords
- Asthma
- Chronic obstructive pulmonary disease
- Lung cancer
- Lung disease
- Lung injury
- MicroRNA
- Pulmonary fibrosis
- Smoking
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
}
Rol de los microARN en las enfermedades pulmonares. / Angulo, Martín; Lecuona, Emilia; Sznajder, Jacob I.
In: Archivos de Bronconeumologia, Vol. 48, No. 9, 01.01.2012, p. 325-330.Research output: Contribution to journal › Short survey
TY - JOUR
T1 - Rol de los microARN en las enfermedades pulmonares
AU - Angulo, Martín
AU - Lecuona, Emilia
AU - Sznajder, Jacob I
PY - 2012/1/1
Y1 - 2012/1/1
N2 - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.
AB - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.
KW - Asthma
KW - Chronic obstructive pulmonary disease
KW - Lung cancer
KW - Lung disease
KW - Lung injury
KW - MicroRNA
KW - Pulmonary fibrosis
KW - Smoking
UR - http://www.scopus.com/inward/record.url?scp=84864832116&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864832116&partnerID=8YFLogxK
U2 - 10.1016/j.arbr.2012.06.015
DO - 10.1016/j.arbr.2012.06.015
M3 - Short survey
VL - 48
SP - 325
EP - 330
JO - Archivos de Bronconeumologia
JF - Archivos de Bronconeumologia
SN - 0300-2896
IS - 9
ER -