Rol de los microARN en las enfermedades pulmonares

Translated title of the contribution: Role of MicroRNAs in Lung Disease

Martín Angulo, Emilia Lecuona, Jacob I Sznajder*

*Corresponding author for this work

Research output: Contribution to journalShort survey

57 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

Original languageSpanish
Pages (from-to)325-330
Number of pages6
JournalArchivos de Bronconeumologia
Volume48
Issue number9
DOIs
StatePublished - Jan 1 2012

Fingerprint

MicroRNAs
Lung Diseases
Small Untranslated RNA
Cell Physiological Phenomena
Pulmonary Fibrosis
Chronic Obstructive Pulmonary Disease
Lung Neoplasms
Asthma
Gene Expression
Therapeutics

Keywords

  • Asthma
  • Chronic obstructive pulmonary disease
  • Lung cancer
  • Lung disease
  • Lung injury
  • MicroRNA
  • Pulmonary fibrosis
  • Smoking

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

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title = "Rol de los microARN en las enfermedades pulmonares",
abstract = "MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.",
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Rol de los microARN en las enfermedades pulmonares. / Angulo, Martín; Lecuona, Emilia; Sznajder, Jacob I.

In: Archivos de Bronconeumologia, Vol. 48, No. 9, 01.01.2012, p. 325-330.

Research output: Contribution to journalShort survey

TY - JOUR

T1 - Rol de los microARN en las enfermedades pulmonares

AU - Angulo, Martín

AU - Lecuona, Emilia

AU - Sznajder, Jacob I

PY - 2012/1/1

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N2 - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

AB - MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

KW - Asthma

KW - Chronic obstructive pulmonary disease

KW - Lung cancer

KW - Lung disease

KW - Lung injury

KW - MicroRNA

KW - Pulmonary fibrosis

KW - Smoking

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JF - Archivos de Bronconeumologia

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