Abstract
MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.
Translated title of the contribution | Role of MicroRNAs in Lung Disease |
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Original language | Spanish |
Pages (from-to) | 325-330 |
Number of pages | 6 |
Journal | Archivos de Bronconeumologia |
Volume | 48 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2012 |
Keywords
- Asthma
- Chronic obstructive pulmonary disease
- Lung cancer
- Lung disease
- Lung injury
- MicroRNA
- Pulmonary fibrosis
- Smoking
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine