Rol de los microARN en las enfermedades pulmonares

Translated title of the contribution: Role of MicroRNAs in Lung Disease

Martín Angulo, Emilia Lecuona, Jacob Iasha Sznajder*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

67 Scopus citations

Abstract

MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively regulate gene expression. They actively participate in the modulation of important cell physiological processes and are involved in the pathogenesis of lung diseases such as lung cancer, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease. A better understanding of the role that miRNAs play in these diseases could lead to the development of new diagnostic and therapeutic tools. In this review, we discuss the role of some miRNAs in different lung diseases as well as the possible future of these discoveries in clinical applications.

Translated title of the contributionRole of MicroRNAs in Lung Disease
Original languageSpanish
Pages (from-to)325-330
Number of pages6
JournalArchivos de Bronconeumologia
Volume48
Issue number9
DOIs
StatePublished - Sep 2012

Keywords

  • Asthma
  • Chronic obstructive pulmonary disease
  • Lung cancer
  • Lung disease
  • Lung injury
  • MicroRNA
  • Pulmonary fibrosis
  • Smoking

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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