Role of Neurohormonal Modulators in Heart Failure with Relatively Preserved Systolic Function

Jonathan A. Rapp, Mihai Gheorghiade*

*Corresponding author for this work

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

"Cardiovascular disease remains the leading cause of mortality in the developed world. It is estimated that 5 million Americans suffer from heart failure (HF), and roughly 550,000 new cases are diagnosed annually. Studies have found that 40% to 71% of patients who have HF have relatively preserved systolic functions, or diastolic heart failure (DHF). Although there are abundant data to guide the treatment of heart failure and systolic dysfunction, evidence-based data are lacking in the management of DHF. This article examines the role of neurohormonal modulators in the management of DHF.".

Original languageEnglish (US)
Pages (from-to)77-93
Number of pages17
JournalHeart Failure Clinics
Volume1
Issue number1
DOIs
StatePublished - Apr 1 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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