Role of regional neurotransmitter receptors in corticotropin-releasing factor (CRF)-mediated modulation of fear conditioning

Jelena Radulovic*, Andre Fischer, Ulrike Katerkamp, Joachim Spiess

*Corresponding author for this work

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

We have demonstrated previously that stimulation of hippocampal corticotropin-releasing factor (CRF) receptors enhances, whereas stimulation of CRF receptors in the lateral intermediate septum impairs learning, as indicated by fear conditioning. Here, we report that the action of CRF within the hippocampus and lateral septum require muscarinic and D2 receptors, respectively. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)707-710
Number of pages4
JournalNeuropharmacology
Volume39
Issue number4
DOIs
StatePublished - Mar 15 2000

Keywords

  • CRF
  • Dopamine receptors
  • Hippocampus
  • Lateral septum
  • Learning
  • Muscarinic receptors

ASJC Scopus subject areas

  • Pharmacology
  • Cellular and Molecular Neuroscience

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