Role of the RIP140 corepressor in metabolic regulation

Malcolm G. Parker, Mark Christian, Evangelos Kiskinis, Asha Seth, Donna Nichol, Roger White

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Energy homeostasis depends on the expression of metabolic gene network that control the activity and anabolic and catabolic pathways. A number of nuclear receptors regulate transcription from these gene networks in metabolic tissues. Their transcriptional activity varies according to the recruitment of coactivators or corepressors. The function of the corepressor RIP140 in suppressing the expression of catabolic gene networks in adipose and muscle is the focus of this review.

Original languageEnglish (US)
Title of host publicationNR Coregulators and Human Diseases
PublisherWorld Scientific Publishing Co.
Pages356-369
Number of pages14
ISBN (Electronic)9789812819178
ISBN (Print)9812705368, 9789812705365
DOIs
StatePublished - Jan 1 2008

ASJC Scopus subject areas

  • Medicine(all)

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