Necrotic cells release HMGB1 as a danger signal to activate the immune system. In this issue of Immunity, Kazama et al. (2008) identify a mechanism that determines whether HMGB1 is tolerogenic or immunogenic.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Jul 18 2008|
ASJC Scopus subject areas
- Immunology and Allergy
- Infectious Diseases