ROS links glucose metabolism to breast cancer stem cell and emt phenotype

Michael S. Schieber, Navdeep Chandel*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

81 Scopus citations

Abstract

Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decreased reactive oxygen species levels.

Original languageEnglish (US)
Pages (from-to)265-267
Number of pages3
JournalCancer Cell
Volume23
Issue number3
DOIs
StatePublished - Mar 18 2013

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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