RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae

Christina L. Cordero, Shanmuga Sozhamannan, Karla J. Fullner Satchell*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin.

Original languageEnglish (US)
Pages (from-to)2289-2292
Number of pages4
JournalJournal of clinical microbiology
Volume45
Issue number7
DOIs
StatePublished - Jul 2007

ASJC Scopus subject areas

  • Microbiology (medical)

Fingerprint Dive into the research topics of 'RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae'. Together they form a unique fingerprint.

Cite this