Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls

Lee Friedman; Larry A. Abel; John A. Jesberger; Amjad Malki; Herbert Y. Meltzer

doi:10.1016/0006-3223(92)90155-S

Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls

Lee Friedman^*, Larry A. Abel, John A. Jesberger, Amjad Malki, Herbert Y. Meltzer

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.

Original language	English (US)
Pages (from-to)	1110-1118
Number of pages	9
Journal	Biological psychiatry
Volume	31
Issue number	11
DOIs	https://doi.org/10.1016/0006-3223(92)90155-S
State	Published - Jun 1 1992

Funding

This research was supported by grants from the USPHS (MH 47574, MH 41684, and MH 41594), the Scottish Rite Schizophrenia Research Program, an unrestricted grant to Indiana University by Research to Prevent Blindness, the Sawyer Foundations, and by the Department of Veterans Affairs. HYM is a recipient of a USPHS Research Career Scientist Award (MH 47808).

ASJC Scopus subject areas

Biological Psychiatry

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10.1016/0006-3223(92)90155-S

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title = "Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls",

abstract = "Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.",

author = "Lee Friedman and Abel, {Larry A.} and Jesberger, {John A.} and Amjad Malki and Meltzer, {Herbert Y.}",

note = "Funding Information: This research was supported by grants from the USPHS (MH 47574, MH 41684, and MH 41594), the Scottish Rite Schizophrenia Research Program, an unrestricted grant to Indiana University by Research to Prevent Blindness, the Sawyer Foundations, and by the Department of Veterans Affairs. HYM is a recipient of a USPHS Research Career Scientist Award (MH 47808).",

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AU - Friedman, Lee

AU - Abel, Larry A.

AU - Jesberger, John A.

AU - Malki, Amjad

AU - Meltzer, Herbert Y.

N1 - Funding Information: This research was supported by grants from the USPHS (MH 47574, MH 41684, and MH 41594), the Scottish Rite Schizophrenia Research Program, an unrestricted grant to Indiana University by Research to Prevent Blindness, the Sawyer Foundations, and by the Department of Veterans Affairs. HYM is a recipient of a USPHS Research Career Scientist Award (MH 47808).

PY - 1992/6/1

Y1 - 1992/6/1

N2 - Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.

AB - Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.

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ER -

Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls

Abstract

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ASJC Scopus subject areas

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