Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls

Lee Friedman*, Larry A. Abel, John A. Jesberger, Amjad Malki, Herbert Y. Meltzer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.

Original languageEnglish (US)
Pages (from-to)1110-1118
Number of pages9
JournalBiological psychiatry
Volume31
Issue number11
DOIs
StatePublished - Jun 1 1992

ASJC Scopus subject areas

  • Biological Psychiatry

Fingerprint Dive into the research topics of 'Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls'. Together they form a unique fingerprint.

Cite this