Abstract
Two types of saccadic intrusions into smooth pursuit eye tracking, anticipatory saccades (AS), and square wave jerks (SWJ), were measured in 23 patients with schizophrenia, 16 patients with affective disorder, and 21 normal controls. Constant velocity (5° and 20°/sec) predictable targets were employed. High resolution infrared oculography was employed to record eye movements. Although most subjects had at least one SWJ, there were no significant group differences, and the highest individual rates of SWJ were seen in the normal control group. On the other hand, AS were never seen in normals, but were present in 25%-44% of patients with either schizophrenia or affective disorder. Both patient groups had significantly more AS than controls, but the two patient groups were not significantly different.
Original language | English (US) |
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Pages (from-to) | 1110-1118 |
Number of pages | 9 |
Journal | Biological psychiatry |
Volume | 31 |
Issue number | 11 |
DOIs | |
State | Published - Jun 1 1992 |
Funding
This research was supported by grants from the USPHS (MH 47574, MH 41684, and MH 41594), the Scottish Rite Schizophrenia Research Program, an unrestricted grant to Indiana University by Research to Prevent Blindness, the Sawyer Foundations, and by the Department of Veterans Affairs. HYM is a recipient of a USPHS Research Career Scientist Award (MH 47808).
ASJC Scopus subject areas
- Biological Psychiatry