Safety and Efficacy of Long-Acting Liposomal Bupivacaine Plus Bupivacaine Hydrochloride for Dorsal Penile Block During Ambulatory Pediatric Urologic Surgery

Andrew T. Gabrielson*, Logan Galansky, Tamir Sholklapper, Isabella Florissi, Chad Crigger, Kelly Harris, Nora Haney, Hiten D. Patel, Ming Hsien Wang, Charlotte Wu, John P. Gearhart, Heather N. Di Carlo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

This study evaluates the tolerability and efficacy of preoperative dorsal penile nerve block with Exparel plus bupivacaine hydrochloride in children>6 years old undergoing ambulatory urologic surgery. We demonstrate that the drug combination is well-tolerated, with appropriate analgesic efficacy in the recovery room as well as at 48-hour and 10-14 day follow-up periods. These preliminary data justify the need to perform a prospective, randomized trial comparing Exparel plus bupivacaine hydrochloride to other common local anesthetic regimens used in pediatric urologic surgery.

Original languageEnglish (US)
Pages (from-to)190-193
Number of pages4
JournalUrology
Volume176
DOIs
StatePublished - Jun 2023

ASJC Scopus subject areas

  • Urology

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