Safety of the new macrolide immunomodulators

N. Robinson, P. Singri, K. B. Gordon*

*Corresponding author for this work

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

With the wide acceptance of cyclosporine in the treatment of skin disease, there has been an effort to find new immunomodulating agents with superior safety profiles for use in dermatology. Among the most promising of the classes are the new macrolide immunomodulators, including tacrolimus and pimecrolimus. Of these, only tacrolimus has had widespread use for nondermatologic indications, primarily solid organ transplantation. Both of these agents have been studied for inflammatory diseases of the skin. In this article, we review the systemic and topical toxicities of these macrolide immunomodulators.

Original languageEnglish (US)
Pages (from-to)242-249
Number of pages8
JournalSeminars in cutaneous medicine and surgery
Volume20
Issue number4
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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