Safety of therapy for allergic symptoms during pregnancy

P. Greenberger, R. Patterson

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


We undertook a literature review to document whether certain therapeutic measures could be considered safe during pregnancy in the allergic patient. With the possible exception of brompheniramine, the commonly used antihistamine drugs appear to be safe during pregnancy. The bronchodilators ephedrine and theophylline also appear to be safe, as does cromolyn. Corticosteroids do not appear to have adverse effects in pregnancy beyond those well recognized in nonpregnant patients. Because side effects are reduced when steroids are administered as aerosols in the nose or lung, these preparations seem well suited for use in pregnancy. The safety of allergic immunotherapy has been confirmed. For asthma, annual influenza vaccination is indicated.

Original languageEnglish (US)
Pages (from-to)234-237
Number of pages4
JournalAnnals of internal medicine
Issue number2
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Internal Medicine

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