Salmon-patch hemorrhages after central retinal artery occlusion in sickle cell disease

Lee M. Jampol*, Patrick Condon, Rutheva Dizon Moore, Graham Serjeant, Joel A. Schulman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


In two patients with sickle cell disease (one hemoglobin SC and one hemoglobin SS), central retinal artery occlusions developed. In one case, the occlusion followed a retrobulbar injection of lidocaine hydrochloride. Although the central retinal artery reperfused in each patient, many secondary peripheral retinal arteriolar occlusions remained. During the subsequent days, multiple salmon-patch hemorrhages developed in the distribution of these occluded arterioles. In one patient, the salmon-patch hemorrhages evolved into atrophic schisis cavities. These unusual cases allowed us to document the origin of salmon-patch hemorrhages after peripheral retinal arteriolar occlusions. The development of the hemorrhages was a delayed phenomenon that occurred hours to days after the initial vascular occlusion. Reperfusion of the damaged ischemic vessels with a blowout of the wall of the vessels seems the most likely explanation for this phenomenon.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalArchives of ophthalmology
Issue number2
StatePublished - Feb 1981

ASJC Scopus subject areas

  • Ophthalmology


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