Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women

Gail F. Shust; Jennifer Jao; Gabriela Rodriguez-Caprio; Roberto Posada; Katherine T. Chen; Amelia Averitt; Rhoda S. Sperling

doi:10.1093/jpids/pit019

Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women

Gail F. Shust^*, Jennifer Jao, Gabriela Rodriguez-Caprio, Roberto Posada, Katherine T. Chen, Amelia Averitt, Rhoda S. Sperling

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Combination antiretroviral therapy in pregnant women with human immunodeficiency virus has dramatically decreased maternal-to-child transmission. Highly treatment-experienced pregnant patients have limited effective treatment options due to past toxicities and viral resistance.We present 8 pregnancies in 7 perinatally infected women successfully treated with salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide.

Original language	English (US)
Pages (from-to)	246-250
Number of pages	5
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	3
Issue number	3
DOIs	https://doi.org/10.1093/jpids/pit019
State	Published - Sep 1 2014

Keywords

Darunavir
Enfuvirtide
Etravirine
Pregnancy
Raltegravir

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Infectious Diseases

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10.1093/jpids/pit019

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Shust, Gail F. ; Jao, Jennifer ; Rodriguez-Caprio, Gabriela ; Posada, Roberto ; Chen, Katherine T. ; Averitt, Amelia ; Sperling, Rhoda S. / Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women. In: Journal of the Pediatric Infectious Diseases Society. 2014 ; Vol. 3, No. 3. pp. 246-250.

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abstract = "Combination antiretroviral therapy in pregnant women with human immunodeficiency virus has dramatically decreased maternal-to-child transmission. Highly treatment-experienced pregnant patients have limited effective treatment options due to past toxicities and viral resistance.We present 8 pregnancies in 7 perinatally infected women successfully treated with salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide.",

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Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women. / Shust, Gail F.; Jao, Jennifer; Rodriguez-Caprio, Gabriela; Posada, Roberto; Chen, Katherine T.; Averitt, Amelia; Sperling, Rhoda S.

In: Journal of the Pediatric Infectious Diseases Society, Vol. 3, No. 3, 01.09.2014, p. 246-250.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women

AU - Shust, Gail F.

AU - Jao, Jennifer

AU - Rodriguez-Caprio, Gabriela

AU - Posada, Roberto

AU - Chen, Katherine T.

AU - Averitt, Amelia

AU - Sperling, Rhoda S.

N1 - Publisher Copyright: © The Author 2013.

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Combination antiretroviral therapy in pregnant women with human immunodeficiency virus has dramatically decreased maternal-to-child transmission. Highly treatment-experienced pregnant patients have limited effective treatment options due to past toxicities and viral resistance.We present 8 pregnancies in 7 perinatally infected women successfully treated with salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide.

AB - Combination antiretroviral therapy in pregnant women with human immunodeficiency virus has dramatically decreased maternal-to-child transmission. Highly treatment-experienced pregnant patients have limited effective treatment options due to past toxicities and viral resistance.We present 8 pregnancies in 7 perinatally infected women successfully treated with salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide.

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KW - Etravirine

KW - Pregnancy

KW - Raltegravir

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Salvage regimens containing darunavir, etravirine, raltegravir, or enfuvirtide in highly treatment-experienced perinatally infected pregnant women

Abstract

Keywords

ASJC Scopus subject areas

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