Sarcoidosis in Children: Differentiation from Juvenile Rheumatoid Arthritis

S. B. Mallory, A. S. Paller, B. C. Ginsburg, I. D. McCrossin, R. Abernathy

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Abstract: Sarcoidosis is rare in young children. and is characterized by skin. joint. and eye changes. Differentiated clinically from juvenile rheumatoid ar‐ thritis (JRA) by milder constitutional symptoms and characteristic joint abnor‐ malities. sareoidosis is confirmed by demonstrating noncaseating granulomas in skin. conjunctival, or synovial biopsies. Recent reports have shown children with features of both sarcoidosis and juvenile rheumatoid arthritis. some with similarly affected family members. We cared for four children with sarcoidosis and severe joint manifestations. Two had a personal or family history of JRA. Three of the four children had ichthyosiform cutaneous manifestations. which may suggest an association between severe joint disease and ichthyosiform changes. Because of the difficulty in making a diagnosis on clinical grounds alone. biopsy of cutaneouslesions is recommended in children with these symptoms.

Original languageEnglish (US)
Pages (from-to)313-319
Number of pages7
JournalPediatric dermatology
Issue number4
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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