SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association

Pei Ni Jone, Anitha John, Matthew E. Oster, Kiona Allen, Adrianna H. Tremoulet, Elizabeth V. Saarel, Linda M. Lambert, Shelley D. Miyamoto, Sarah D. De Ferranti

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19) resulted in a global pandemic and has overwhelmed health care systems worldwide. In this scientific statement, we describe the epidemiology, pathophysiology, clinical presentations, treatment, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome in children and young adults with a focus on cardiovascular manifestations and complications. We review current knowledge about the health consequences of this illness in children and young adults with congenital and acquired heart disease, the public health burden and health disparities of this infection in these populations, and vaccine-associated myocarditis.

Original languageEnglish (US)
Pages (from-to)E1037-E1052
JournalCirculation
Volume145
Issue number19
DOIs
StatePublished - May 10 2022

Keywords

  • AHA Scientific Statements
  • COVID-19
  • SARS-CoV-2
  • child
  • multisystem inflammatory syndrome in children
  • treatment outcome
  • young adult

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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