SCALING LAWS AND THE EFFECTS OF CONCENTRATION POLARIZATION ON THE PERMEABILITY OF HYALURONIC ACID.

Mark Johnson*, Roger Kamm, C. Ross Ethier, Tim Pedley

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

20 Scopus citations

Abstract

Investigators have modeled the hydraulic permeability of hyaluronic acid using a fiber matrix model such as developed by J. Happel. However, C. R. Ethier found that the concentration dependence of the sedimentation rate of hyaluronic acid is inconsistent with the predictions of the fiber matrix model and with perfusion measurements of the hydraulic permeability. These discrepancies are investigated and a tentative explanation provided. The discrepancy found between the predictions of the fiber matrix model and the results of perfusion studies may be due to concentration polarization. This process was modeled and examined experimentally. The experimental results are in qualitative agreement with the theory.

Original languageEnglish (US)
Pages (from-to)427-441
Number of pages15
JournalPCH. Physicochemical hydrodynamics
Volume9
Issue number3-4
StatePublished - Dec 1 1987
Eventth Int Conf - Oxford, Engl
Duration: Apr 6 1987Apr 8 1987

ASJC Scopus subject areas

  • Engineering(all)

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