Abstract
A tumorigenic human cell line was derived from a patient with metastatic melanoma. Cells were treated with adriamycin or actinomycin D in order to assess morphological alterations induced by these anticancer agents using SEM and TEM. TEM of colonies treated in soft agar for 24 hours with either 1. 0 mu g/ml adriamycin or 1. 0 mu g/ml actinomycin D showed major morphological effects identified by increased cytoplasmic vacuolization and nuclear disintegration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 983-995 |
| Number of pages | 13 |
| Journal | Scanning Electron Microscopy |
| Volume | v |
| Issue number | pt 2 |
| State | Published - 1983 |
ASJC Scopus subject areas
- Control and Systems Engineering
- Biophysics