Scedosporium apiospermum fungemia in a lung transplant recipient

Rishi Raj, Adaani E. Frost*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

Scedosporium apiospermum, the asexual anamorph of the cosmopolitan fungus Pseudallescheria boydii, is emerging as an important cause of disseminated infection in immunocompromised patients. We present our experience with the first reported case of S apiospermum fungemia in a lung transplant patient. Disseminated infection resulted in sepsis, multiorgan failure, and death. Review of the literature highlights the diagnostic difficulties related to the similarities between S apiospermum and Aspergillus sp. This superficial resemblance has a significant impact on clinical outcomes considering the inherent resistance of Scedosporium to amphotericin B, the traditional antifungal of choice for disseminated hyalohyphomycoses.

Original languageEnglish (US)
Pages (from-to)1714-1716
Number of pages3
JournalCHEST
Volume121
Issue number5
DOIs
StatePublished - 2002

Keywords

  • Fungal infection
  • Lung transplantation
  • Pseudallescheria boydii
  • Scedosporium apiospermum

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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