Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959–1961

Cuntong Wang*, Yudong Zhang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Analyzing data from a large-scale, nationally representative sample, this study examines the association between prenatal exposure to the Chinese Famine (1959–1961) and schizophrenia risk in mid-adulthood and its urban/rural-specific and gender-specific patterns. The results showed that the cohort conceived and born during the famine had a higher risk of schizophrenia in mid-adulthood than cohorts conceived and born before or after the famine. In addition, schizophrenia risk was higher for urban residents than for rural residents and higher for females than for males. Drawing on the psychiatric features of late-onset schizophrenia in mid-adulthood, we then offer some theoretical mechanisms to explain the cohort, urban/rural, and gender differences.

Original languageEnglish (US)
Pages (from-to)21-25
Number of pages5
JournalSchizophrenia Research
Volume184
DOIs
StatePublished - Jun 2017

Funding

The research is funded by the Program for Innovation Research in the Central University of Finance and Economics (13CUFE001), the Program for New Century Excellent Talents in University, China (13NCET001), and the Program of the National Social Science Foundation of China (14BRK025).

Keywords

  • Chinese famine
  • Mid-adulthood
  • Prenatal malnutrition
  • Schizophrenia risk

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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