TY - JOUR
T1 - Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959–1961
AU - Wang, Cuntong
AU - Zhang, Yudong
N1 - Funding Information:
The research is funded by the Program for Innovation Research in the Central University of Finance and Economics (13CUFE001), the Program for New Century Excellent Talents in University, China (13NCET001), and the Program of the National Social Science Foundation of China (14BRK025).
Publisher Copyright:
© 2016
PY - 2017/6
Y1 - 2017/6
N2 - Analyzing data from a large-scale, nationally representative sample, this study examines the association between prenatal exposure to the Chinese Famine (1959–1961) and schizophrenia risk in mid-adulthood and its urban/rural-specific and gender-specific patterns. The results showed that the cohort conceived and born during the famine had a higher risk of schizophrenia in mid-adulthood than cohorts conceived and born before or after the famine. In addition, schizophrenia risk was higher for urban residents than for rural residents and higher for females than for males. Drawing on the psychiatric features of late-onset schizophrenia in mid-adulthood, we then offer some theoretical mechanisms to explain the cohort, urban/rural, and gender differences.
AB - Analyzing data from a large-scale, nationally representative sample, this study examines the association between prenatal exposure to the Chinese Famine (1959–1961) and schizophrenia risk in mid-adulthood and its urban/rural-specific and gender-specific patterns. The results showed that the cohort conceived and born during the famine had a higher risk of schizophrenia in mid-adulthood than cohorts conceived and born before or after the famine. In addition, schizophrenia risk was higher for urban residents than for rural residents and higher for females than for males. Drawing on the psychiatric features of late-onset schizophrenia in mid-adulthood, we then offer some theoretical mechanisms to explain the cohort, urban/rural, and gender differences.
KW - Chinese famine
KW - Mid-adulthood
KW - Prenatal malnutrition
KW - Schizophrenia risk
UR - http://www.scopus.com/inward/record.url?scp=85007433708&partnerID=8YFLogxK
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U2 - 10.1016/j.schres.2016.11.030
DO - 10.1016/j.schres.2016.11.030
M3 - Article
C2 - 27894821
AN - SCOPUS:85007433708
SN - 0920-9964
VL - 184
SP - 21
EP - 25
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -
