Schmorl nodes can cause increased 68Ga DOTATATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy

Georgios Z. Papadakis; Corina Millo; Ulas Bagci; Samira M. Sadowski; Constantine A. Stratakis

doi:10.1097/RLU.0000000000001065

Schmorl nodes can cause increased ⁶⁸Ga DOTATATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy

Georgios Z. Papadakis, Corina Millo, Ulas Bagci, Samira M. Sadowski, Constantine A. Stratakis^*

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased ¹⁸F-FDG uptake.We present a case of a patient with history of neuroendocrine tumor, who underwent ⁶⁸Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in ⁶⁸Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors.

Original language	English (US)
Pages (from-to)	249-250
Number of pages	2
Journal	Clinical nuclear medicine
Volume	41
Issue number	3
DOIs	https://doi.org/10.1097/RLU.0000000000001065
State	Published - 2016

Keywords

Ga DOTATATE PET/CT
Inflammation
Neuroendocrine tumor
Schmorl node

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/RLU.0000000000001065

Cite this

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title = "Schmorl nodes can cause increased 68Ga DOTATATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy",

abstract = "Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased 18F-FDG uptake.We present a case of a patient with history of neuroendocrine tumor, who underwent 68Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in 68Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors.",

keywords = "Ga DOTATATE PET/CT, Inflammation, Neuroendocrine tumor, Schmorl node",

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T1 - Schmorl nodes can cause increased 68Ga DOTATATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy

AU - Papadakis, Georgios Z.

AU - Millo, Corina

AU - Bagci, Ulas

AU - Sadowski, Samira M.

AU - Stratakis, Constantine A.

PY - 2016

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AB - Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased 18F-FDG uptake.We present a case of a patient with history of neuroendocrine tumor, who underwent 68Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in 68Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors.

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