SCN3A deficiency associated with increased seizure susceptibility

Keyphrases

• Seizure Susceptibility 100%
• SCN3A 100%
• Loss Function 13%
• Focal Epilepsy 13%
• Biophysical Characterization 6%
• Epilepsy 6%
• Mutant Mice 6%
• Epilepsy Syndrome 6%
• Protein Expression 6%
• Plasma Membrane 6%
• Cell Surface 6%
• Motor Learning 6%
• Seizure 6%
• Acid Activation 6%
• Increased Vulnerability 6%
• Clinical Consequences 6%
• Voltage Clamp 6%
• Voltage-gated Sodium Channel 6%
• SCN1A 6%
• Reduced Protein 6%
• Autonomic Dysfunction 6%
• SCN2A 6%
• Locomotor Activity 6%
• SCN8A 6%
• Sodium Current 6%
• Hyperthermia-induced Seizure 6%
• Spontaneous Seizures 6%
• Active Learning 6%
• Pore-forming 6%
• Whole Exome Sequencing 6%
• Developmental Delay 6%
• Gene Trap 6%
• Heterologous Expression System 6%
• Hyp Mice 6%
• Hypomorphic mutation 6%
• Kainic Acid 6%
• Cell Surface Biotinylation 6%
• Nav1.3 6%
• Flurothyl 6%
• Seizure Behavior 6%

Neuroscience

• SCN3A 100%
• Focal Epilepsy 18%
• Kainic Acid 9%
• Nervous System Dysfunction 9%
• Motor Learning 9%
• Autonomic Nervous System 9%
• Locomotor Activity 9%
• Behavior (Neuroscience) 9%
• Protein Expression 9%
• Voltage Gated Sodium Channel 9%
• SCN8A 9%
• Sodium Current 9%
• Gene Expression System 9%
• Heterologous Expression 9%
• Biotinylation 9%
• Cell Membrane 9%
• Exome Sequencing 9%
• Flurothyl 9%
• Voltage Clamp 9%