Sc(OTf)3-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: An efficient synthesis of 5-alkyl-1,3-oxazolidines

Byungman Kang, Aaron W. Miller, Sandra Goyal, Sonbinh T. Nguyen

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Sc(OTf)3 effectively catalyzes the condensation of 2-alkyl-N-tosylaziridine with a wide variety of aldehydes and ketones, producing 5-alkyl-1,3-oxazolidines in good yields and excellent regioselectivity at catalyst loadings as low as 1 mol%.

Original languageEnglish (US)
Pages (from-to)3928-3930
Number of pages3
JournalChemical Communications
Issue number26
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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