Abstract
Diabetic kidney disease (DKD) is one of the microvascular complications of diabetes. Annual screening with a urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) is recommended at diagnosis for type 2 diabetes and 5 years after diagnosis for type 1 diabetes. DKD is a clinical diagnosis usually made when there is presence of persistent albuminuria and a reduced eGFR (estimated glomerular filtration rate), in the setting of prolonged duration of diabetes and diabetic retinopathy. Several urinary and serum biomarkers have been proposed for early detection of DKD. Genetic markers associated with predisposition to diabetic kidney disease have been identified.
Original language | English (US) |
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Title of host publication | Diabetes and Kidney Disease, Second Edition |
Publisher | Springer International Publishing |
Pages | 185-218 |
Number of pages | 34 |
ISBN (Electronic) | 9783030860202 |
ISBN (Print) | 9783030860196 |
DOIs | |
State | Published - Jan 1 2022 |
Keywords
- Albuminuria
- Biomarkers
- Diagnosis
- Genetic markers
- Screening
ASJC Scopus subject areas
- General Medicine