Screening, Early Diagnosis, Genetic Markers and Predictors of Progression

Jennifer Tuazon*, Janis Cho

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Diabetic kidney disease (DKD) is one of the microvascular complications of diabetes. Annual screening with a urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) is recommended at diagnosis for type 2 diabetes and 5 years after diagnosis for type 1 diabetes. DKD is a clinical diagnosis usually made when there is presence of persistent albuminuria and a reduced eGFR (estimated glomerular filtration rate), in the setting of prolonged duration of diabetes and diabetic retinopathy. Several urinary and serum biomarkers have been proposed for early detection of DKD. Genetic markers associated with predisposition to diabetic kidney disease have been identified.

Original languageEnglish (US)
Title of host publicationDiabetes and Kidney Disease, Second Edition
PublisherSpringer International Publishing
Pages185-218
Number of pages34
ISBN (Electronic)9783030860202
ISBN (Print)9783030860196
DOIs
StatePublished - Jan 1 2022

Keywords

  • Albuminuria
  • Biomarkers
  • Diagnosis
  • Genetic markers
  • Screening

ASJC Scopus subject areas

  • General Medicine

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