@article{9969493c49a74861a07b4175853afff4,
title = "Searching for the cause of Kawasaki disease - Cytoplasmic inclusion bodies provide new insight",
abstract = "Kawasaki disease (KD) has emerged as the most common cause of acquired heart disease in children in the developed world. The cause of KD remains unknown, although an as-yet unidentified infectious agent might be responsible. By determining the causative agent, we can improve diagnosis, therapy and prevention of KD. Recently, identification of an antigen-driven IgA response that was directed at cytoplasmic inclusion bodies in KD tissues has provided new insights that could unlock the mysteries of KD.",
author = "Rowley, {Anne H.} and Baker, {Susan C.} and Orenstein, {Jan M.} and Shulman, {Stanford T.}",
note = "Funding Information: Research in the laboratories of N.A. and S.E.H. was supported by several grants from the Department of Biotechnology, Ministry of Science & Technology, Government of India. Research in the laboratories of U.D. and J.H. was supported by grants from the German Research Foundation (SFB479, TP A1), the European Community (European virtual institute for functional genomics of bacterial pathogens; CEE LSHB-CT-2005-512,061) and the Bavarian Research Foundation. Funding Information: Research in the laboratory of A.H.R. is supported by National Institutes of Health (grant HL63771) and The Kawasaki Disease Fund of the Children{\textquoteright}s Memorial Hospital. Research in the laboratory of S.C.B. is supported by the Research Funding Committee of Loyola University Stritch School of Medicine (grant LU109703). Funding Information: To respond to such needs, the founders of TDr devised a set of novel institutional formulae that were inspired by some of the new public policy forums that were taking shape at the time in other arenas, particularly the Consultative Group for International Agricultural research4. Distinctive features of TDr included sponsorship by multiple UN institutions. Although TDr was initially sponsored by the World Health Organization (WHO), the United Nations Development Programme was also involved from the beginning and joined formally as a co-sponsor in 1976, followed by the World Bank in 1977 and the United Nations Children{\textquoteright}s Fund (UNICEF) in 2003. Another innovation was the equal representation of donor and recipient governments on TDr{\textquoteright}s governing body, the Joint Coordinating Board (JCB), which was created in 1978 (ReF. 5). Meanwhile, the scientific and Technical Advisory Committee (sTAC), an independent technical-oversight body, enlisted leading scientists not only from global centres of expertise but also from disease-endemic regions and industry. This kind of cooperation bestowed research credibility and helped make TDr a forerunner of the public–private partnerships (PPPs) that would emerge around the turn of the millennium6–9.",
year = "2008",
month = may,
doi = "10.1038/nrmicro1853",
language = "English (US)",
volume = "6",
pages = "394--401",
journal = "Nature Reviews Microbiology",
issn = "1740-1526",
publisher = "Nature Publishing Group",
number = "5",
}
