Searching for the cause of Kawasaki disease - Cytoplasmic inclusion bodies provide new insight

Anne H. Rowley*, Susan C. Baker, Jan M. Orenstein, Stanford T. Shulman

*Corresponding author for this work

Research output: Contribution to journalArticle

93 Scopus citations

Abstract

Kawasaki disease (KD) has emerged as the most common cause of acquired heart disease in children in the developed world. The cause of KD remains unknown, although an as-yet unidentified infectious agent might be responsible. By determining the causative agent, we can improve diagnosis, therapy and prevention of KD. Recently, identification of an antigen-driven IgA response that was directed at cytoplasmic inclusion bodies in KD tissues has provided new insights that could unlock the mysteries of KD.

Original languageEnglish (US)
Pages (from-to)394-401
Number of pages8
JournalNature Reviews Microbiology
Volume6
Issue number5
DOIs
StatePublished - May 1 2008

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Microbiology(all)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Searching for the cause of Kawasaki disease - Cytoplasmic inclusion bodies provide new insight'. Together they form a unique fingerprint.

Cite this