Second-sphere coordination

Françisco M. Raymo*, J. Fraser Stoddart

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


The design and synthesis of artificial receptors, able to recognize and bind transition metal complexes, is an area of growing interest in supramolecular chemistry. Macrocyclic hosts such as crown ethers, cyclodextrins, and cyclophanes have been employed to generate second-sphere adducts with numerous transition metal complexes as a result of non-covalent bonding interactions, such as hydrogen bonding, π-π stacking, and hydrophobic interactions. The effect of second-sphere coordination on the chemical, electrochemical, and photochemical properties of the adducts, as well as on their geometries in solution and in the solid state, has been investigated; these investigations have demonstrated the potential of second-sphere coordination in modulating the behavior of transition rnetal complexes bv designed external intervention.

Original languageEnglish (US)
Pages (from-to)981-990
Number of pages10
JournalChemische Berichte
Issue number9
StatePublished - 1996


  • Molecular recognition Second-sphere coordination
  • Transition metals

ASJC Scopus subject areas

  • Chemistry(all)


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