Sedentary behavior and blood pressure control among osteoarthritis initiative participants

M. W. Sohn; L. M. Manheim; R. W. Chang; P. Greenland; M. C. Hochberg; M. C. Nevitt; P. A. Semanik; D. D. Dunlop

doi:10.1016/j.joca.2014.07.007

Sedentary behavior and blood pressure control among osteoarthritis initiative participants

M. W. Sohn, L. M. Manheim, R. W. Chang, P. Greenland, M. C. Hochberg, M. C. Nevitt, P. A. Semanik, D. D. Dunlop

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

OBJECTIVE: To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.

DESIGN: We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and "elevated BP" defined as BP ≥ 130/85 mm Hg.

RESULTS: For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.

CONCLUSION: A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.

Original language	English (US)
Pages (from-to)	1234-1240
Number of pages	7
Journal	Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Volume	22
Issue number	9
DOIs	https://doi.org/10.1016/j.joca.2014.07.007
State	Published - Sep 1 2014

Funding

This study was funded by the NIH / NIAMS (grants R01AR052912 and P60AR064464 ) and by Falk Medical Trust Research Funds . The sponsors played no role in the design of the study, analysis or interpretation of findings, or drafting the manuscript and did not review or approve the manuscript prior to submission. The authors assume full responsibility for the accuracy and completeness of the ideas presented.

Keywords

Blood pressure
Osteoarthritis
Physical activity
Sedentary lifestyle

ASJC Scopus subject areas

Biomedical Engineering
Rheumatology
Orthopedics and Sports Medicine

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10.1016/j.joca.2014.07.007

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title = "Sedentary behavior and blood pressure control among osteoarthritis initiative participants",

abstract = "OBJECTIVE: To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.DESIGN: We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and {"}elevated BP{"} defined as BP ≥ 130/85 mm Hg.RESULTS: For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.CONCLUSION: A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.",

keywords = "Blood pressure, Osteoarthritis, Physical activity, Sedentary lifestyle",

author = "Sohn, {M. W.} and Manheim, {L. M.} and Chang, {R. W.} and P. Greenland and Hochberg, {M. C.} and Nevitt, {M. C.} and Semanik, {P. A.} and Dunlop, {D. D.}",

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doi = "10.1016/j.joca.2014.07.007",

language = "English (US)",

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T1 - Sedentary behavior and blood pressure control among osteoarthritis initiative participants

AU - Sohn, M. W.

AU - Manheim, L. M.

AU - Chang, R. W.

AU - Greenland, P.

AU - Hochberg, M. C.

AU - Nevitt, M. C.

AU - Semanik, P. A.

AU - Dunlop, D. D.

N1 - Publisher Copyright: Published by Elsevier Ltd.

PY - 2014/9/1

Y1 - 2014/9/1

N2 - OBJECTIVE: To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.DESIGN: We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and "elevated BP" defined as BP ≥ 130/85 mm Hg.RESULTS: For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.CONCLUSION: A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.

AB - OBJECTIVE: To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.DESIGN: We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and "elevated BP" defined as BP ≥ 130/85 mm Hg.RESULTS: For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.CONCLUSION: A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.

KW - Blood pressure

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KW - Physical activity

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JO - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

JF - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

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ER -

Sedentary behavior and blood pressure control among osteoarthritis initiative participants

Abstract

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