Sedentary Bout Patterns and Metabolic Health in the Hispanic Community Health Study/Study of Latino Youth (SOL Youth)

Jordan A. Carlson*, Paul R. Hibbing, Bethany Forseth, Keith M. Diaz, Daniela Sotres-Alvarez, Carolina M. Bejarano, Andrea T. Duran, Sheila F. Castañeda, Melawhy L. Garcia, Krista M. Perreira, Martha L. Daviglus, Linda Van Horn, Marc D. Gellman, Carmen R. Isasi, Jianwen Cai, Alan M. Delamater, Vincent S. Staggs, John Thyfault, Linda C. Gallo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: There is limited evidence on the potential negative metabolic health impacts of prolonged and uninterrupted sedentary bouts in structurally disadvantaged youth. This study investigated associations between sedentary bout variables and metabolic health markers in the Hispanic Community Health Study/SOL Youth (Study of Latino Youth). METHODS AND RESULTS: SOL Youth was a population-based cohort of 1466 youth (age range, 8–16 years; 48.5% female); 957 youth were included in the analytic sample based on complete data. Accelerometers measured moderate-to-vigorous physical activity (MVPA), total sedentary time, and sedentary bout patterns (daily time spent in sedentary bouts ≥30 minutes, median sedentary bout duration, and number of daily breaks from sedentary time). Clinical measures included body mass index, waist circumference, fasting glucose, glycated hemoglobin, fasting insulin, and the homeostasis model assessment of insulin resistance. After adjusting for sociodemographics, total sedentary time, and MVPA, longer median bout durations and fewer sedentary breaks were associated with a greater body mass index percentile (bbouts =0.09 and bbreaks =−0.18), waist circumference (bbouts =0.12 and bbreaks =−0.20), and fasting insulin (bbouts =0.09 and bbreaks =−0.21). Fewer breaks were also associated with a greater homeostasis model assessment of insulin resistance (b=−0.21). More time in bouts lasting ≥30 minutes was associated with a greater fasting glucose (b=0.18) and glycated hemoglobin (b=0.19). CONCLUSIONS: Greater accumulation of sedentary time in prolonged and uninterrupted bouts had adverse associations with adiposity and glycemic control over and above total sedentary time and MVPA. Findings suggest interventions in Hispanic/ Latino youth targeting both ends of the activity spectrum (more MVPA and less prolonged/uninterrupted sedentary patterns) may provide greater health benefits than those targeting only MVPA.

Original languageEnglish (US)
Article numbere028495
JournalJournal of the American Heart Association
Volume12
Issue number18
DOIs
StatePublished - Sep 19 2023

Funding

The SOL Youth study was supported by Grant Number R01HL102130 from the National Heart, Lung, and Blood Institute. The children in SOL Youth are drawn from the study of adults: The HCHS/SOL, which was supported by contracts from the National Heart, Lung, and Blood Institute to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), University of Illinois at Chicago (HHSN268201300002I)/Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the National Heart, Lung, and Blood Institute: National Center on Minority Health and Health Disparities, the National Institute of Deafness and Other Communications Disorders, the National Institute of Dental and Craniofacial Research, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke, and the Office of Dietary Supplements. Additional support was provided by the Life Course Methodology Core of the New York Regional Center for Diabetes Translation Research (DK111022– 8786). J.A. Carlson, K.M. Perreira, and D. Sotres-Alvarez received support from the National Heart, Lung, and Blood Institute, R01HL148463, 75N92019D00010, and R01HL102130. C.M. Bejarano received support from the Center for Children’s Healthy Lifestyles & Nutrition at Children’s Mercy Kansas City and the University of Kansas Medical Center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute, the National Institutes of Health, or other funders. Additional support was provided by the Life Course Methodology Core of the New York Regional Center for Diabetes Translation Research (DK111022–8786). J.A. Carlson, K.M. Perreira, and D. Sotres-Alvarez received support from the National Heart, Lung, and Blood Institute, R01HL148463, 75N92019D00010, and R01HL102130. C.M. Bejarano received support from the Center for Children’s Healthy Lifestyles & Nutrition at Children’s Mercy Kansas City and the University of Kansas Medical Center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute, the National Institutes of Health, or other funders. The SOL Youth study was supported by Grant Number R01HL102130 from the National Heart, Lung, and Blood Institute. The children in SOL Youth are drawn from the study of adults: The HCHS/SOL, which was supported by contracts from the National Heart, Lung, and Blood Institute to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), University of Illinois at Chicago (HHSN268201300002I)/Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the National Heart, Lung, and Blood Institute: National Center on Minority Health and Health Disparities, the National Institute of Deafness and Other Communications Disorders, the National Institute of Dental and Craniofacial Research, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke, and the Office of Dietary Supplements.

Keywords

  • children
  • glucose
  • insulin
  • obesity
  • physical activity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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