Seeking alternative biological therapies: The future of targeted molecular treatment

Jochen H. Lorch*, Marshall R. Posner, Lori J. Wirth, Robert I. Haddad

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

In recent years targeted therapies have expanded treatment options for patients with squamous cell cancer of the head and neck (SCCHN) considerably and have led to clinically significant benefit. However, the multitude of new targeted drugs that have emerged and are in development also represent a challenge and many years of carefully conducted clinical studies will be needed to explore their full potential. This article summarizes the most important recent developments in the targeted treatment of SCCHN and provides an overview of pathways and promising potential targets that could impact the treatment of patients with SCCHN in the future.

Original languageEnglish (US)
Pages (from-to)447-453
Number of pages7
JournalOral Oncology
Volume45
Issue number4-5
DOIs
StatePublished - Apr 2009
Externally publishedYes

ASJC Scopus subject areas

  • Oral Surgery
  • Oncology
  • Cancer Research

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