Seizure recency and quality of life in adolescents with childhood-onset epilepsy

Christine B. Baca*, Barbara G. Vickrey, Stefanie D. Vassar, Anne T. Berg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Health-related quality of life (HRQOL) is associated with seizure recency among adults with epilepsy. In a prospective, community-based study of long-term outcomes of childhood-onset epilepsy, we evaluated whether worse HRQOL is associated with more recent seizures among children and adolescents with epilepsy. We used the Child Health Questionnaire (CHQ), a generic measure with child and parent-proxy versions, to measure HRQOL. Among 277 children with epilepsy (CWE) assessed 9. years after diagnosis, parent-proxy reported but not child self-reported HRQOL was significantly worse for those having seizures in the prior year than for those who were seizure free ≥ 1 year across the majority of scales. There were no differences between CWE in remission for 1-5. years and those seizure free ≥ 5 years for child and parent-proxy reported HRQOL with the exception of the parent Emotional Impact scale, suggesting that HRQOL differences related to seizure recency level off after the initial year of remission.

Original languageEnglish (US)
Pages (from-to)47-51
Number of pages5
JournalEpilepsy and Behavior
Issue number1
StatePublished - Jan 2012


  • Children and adolescents
  • Epilepsy
  • Health-related quality of life
  • Parent-proxy reports
  • Seizure recency
  • Seizure remission

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


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