Seizures and their outcome in progressive multifocal leukoencephalopathy

Marco A. Lima; Frank W. Drislane; Igor J. Koralnik

doi:10.1212/01.wnl.0000194227.16696.11

Seizures and their outcome in progressive multifocal leukoencephalopathy

Marco A. Lima, Frank W. Drislane, Igor J. Koralnik^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

Seizures are not expected in progressive multifocal leukoencephalopathy (PML), a condition considered to be restricted to the white matter. Review of medical records of 89 patients with possible or proven PML showed an 18% prevalence of seizures. Seizures usually responded well to treatment and did not affect survival. The presence of PML lesions immediately adjacent to the hemispheric cortex was the only risk factor associated with seizures in this population.

Original language	English (US)
Pages (from-to)	262-264
Number of pages	3
Journal	Neurology
Volume	66
Issue number	2
DOIs	https://doi.org/10.1212/01.wnl.0000194227.16696.11
State	Published - Jan 2006

ASJC Scopus subject areas

Clinical Neurology

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10.1212/01.wnl.0000194227.16696.11

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title = "Seizures and their outcome in progressive multifocal leukoencephalopathy",

abstract = "Seizures are not expected in progressive multifocal leukoencephalopathy (PML), a condition considered to be restricted to the white matter. Review of medical records of 89 patients with possible or proven PML showed an 18% prevalence of seizures. Seizures usually responded well to treatment and did not affect survival. The presence of PML lesions immediately adjacent to the hemispheric cortex was the only risk factor associated with seizures in this population.",

author = "Lima, {Marco A.} and Drislane, {Frank W.} and Koralnik, {Igor J.}",

note = "Funding Information: Supported in part by Public Health Service Grants R01 NS/AI 041198 and NS 047029 (I.J.K.) and by the Ellen R. Cavallo research fund. M.A.L. is the recipient of a Fellowship from the National Scientific and Technological Development Council, CNPq- Brazil. ",

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AU - Drislane, Frank W.

AU - Koralnik, Igor J.

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N2 - Seizures are not expected in progressive multifocal leukoencephalopathy (PML), a condition considered to be restricted to the white matter. Review of medical records of 89 patients with possible or proven PML showed an 18% prevalence of seizures. Seizures usually responded well to treatment and did not affect survival. The presence of PML lesions immediately adjacent to the hemispheric cortex was the only risk factor associated with seizures in this population.

AB - Seizures are not expected in progressive multifocal leukoencephalopathy (PML), a condition considered to be restricted to the white matter. Review of medical records of 89 patients with possible or proven PML showed an 18% prevalence of seizures. Seizures usually responded well to treatment and did not affect survival. The presence of PML lesions immediately adjacent to the hemispheric cortex was the only risk factor associated with seizures in this population.

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Seizures and their outcome in progressive multifocal leukoencephalopathy

Abstract

ASJC Scopus subject areas

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