Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy

Richard M. Timms; Paul A. Kvale; Nicholas R. Anthonisen; C. Thomas Boylen; David W. Cugell; Thomas L. Petty; George W. Williams

doi:10.1001/jama.1981.03310490032020

Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy

Richard M. Timms, Paul A. Kvale, Nicholas R. Anthonisen, C. Thomas Boylen, David W. Cugell, Thomas L. Petty, George W. Williams

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The Nocturnal Oxygen Therapy Trial, a study of oxygen therapy in patients with chronic obstructive pulmonary disease, has combined the experience of six centers concerning the selection of patients for oxygen treatment. Forty-five percent of hypoxic patients initially selected for the study improved enough during the one month of outpatient observation to allow suspension of plans to treat them with oxygen. Therefore, long-term oxygen therapy plans should only be made without a month of careful observation. Resting Pao2 values less than 40 mm Hg suggest instability or that chronic obstructive pulmonary disease is not the only cause of the hypoxemia. Nasal prong oxygen flow of 1 to 3 L/min reversed hypoxemia in 95% of stable patients with chronic obstructive pulmonary disease. (JAMA 1981;245:2514-2515).

Original language	English (US)
Pages (from-to)	2514-2515
Number of pages	2
Journal	JAMA: The Journal of the American Medical Association
Volume	245
Issue number	24
DOIs	https://doi.org/10.1001/jama.1981.03310490032020
State	Published - Jun 26 1981
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy",

abstract = "The Nocturnal Oxygen Therapy Trial, a study of oxygen therapy in patients with chronic obstructive pulmonary disease, has combined the experience of six centers concerning the selection of patients for oxygen treatment. Forty-five percent of hypoxic patients initially selected for the study improved enough during the one month of outpatient observation to allow suspension of plans to treat them with oxygen. Therefore, long-term oxygen therapy plans should only be made without a month of careful observation. Resting Pao2 values less than 40 mm Hg suggest instability or that chronic obstructive pulmonary disease is not the only cause of the hypoxemia. Nasal prong oxygen flow of 1 to 3 L/min reversed hypoxemia in 95% of stable patients with chronic obstructive pulmonary disease. (JAMA 1981;245:2514-2515).",

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AU - Timms, Richard M.

AU - Kvale, Paul A.

AU - Anthonisen, Nicholas R.

AU - Boylen, C. Thomas

AU - Cugell, David W.

AU - Petty, Thomas L.

AU - Williams, George W.

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Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy

Abstract

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