Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy

Richard M. Timms, Paul A. Kvale, Nicholas R. Anthonisen, C. Thomas Boylen, David W Cugell, Thomas L. Petty, George W. Williams

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

The Nocturnal Oxygen Therapy Trial, a study of oxygen therapy in patients with chronic obstructive pulmonary disease, has combined the experience of six centers concerning the selection of patients for oxygen treatment. Forty-five percent of hypoxic patients initially selected for the study improved enough during the one month of outpatient observation to allow suspension of plans to treat them with oxygen. Therefore, long-term oxygen therapy plans should only be made without a month of careful observation. Resting Pao2 values less than 40 mm Hg suggest instability or that chronic obstructive pulmonary disease is not the only cause of the hypoxemia. Nasal prong oxygen flow of 1 to 3 L/min reversed hypoxemia in 95% of stable patients with chronic obstructive pulmonary disease. (JAMA 1981;245:2514-2515).

Original languageEnglish (US)
Pages (from-to)2514-2515
Number of pages2
JournalJAMA: The Journal of the American Medical Association
Volume245
Issue number24
DOIs
StatePublished - Jun 26 1981

ASJC Scopus subject areas

  • Medicine(all)

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    Timms, R. M., Kvale, P. A., Anthonisen, N. R., Boylen, C. T., Cugell, D. W., Petty, T. L., & Williams, G. W. (1981). Selection of Patients With Chronic Obstructive Pulmonary Disease for Long-term Oxygen Therapy. JAMA: The Journal of the American Medical Association, 245(24), 2514-2515. https://doi.org/10.1001/jama.1981.03310490032020