Selective feticide by embolization in twin-twin transfusion syndrome: A report of two cases

Catherine Donner, Shohreh Shahabi*, Dominique Thomas, Jean Christophe Noël, Christine Kirkpatrick, Michel Van Rysselberghe, Corinne Hubinon, Daniele Vermeylen, Louise Masters, Frédéric Rodesch

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


BACKGROUND: The early development of complications in twin-twin transfusion syndrome is a poor prognostic sign. For this reason, new techniques for intrauterine therapy are being developed: invasive options, such as selective feticide of one of the twins, have been reported. CASES: Two cases of twin-twin transfusion syndrome in the late second trimester were treated by selective feticide using vascular embolization to the more severely damaged fetus. In one case the embolized fetus was a hydropic recipient with a normal cotwin; in the other, the donor fetus was affected by bilateral hydrocephalus. These fetuses underwent ultrasound-guided embolization using a bolus of histoacryl injected into the umbilical vein and fetal heart. Both patients went on to deliver healthy singletons in the third trimester. CONCLUSION: In twin-twin transfusion syndrome of early onset, embolization may help one of the twins survive. This technique is neither time-consuming nor expensive and does not require a general anesthetic.

Original languageEnglish (US)
Pages (from-to)747-750
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number11
StatePublished - Nov 1 1997


  • Embolization, therapeutic
  • Twin transfusion syndrome
  • Twins

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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