Self-assembled monolayers that transduce enzymatic activities to electrical signals

Woon Seok Yeo, Milan Mrksich*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


A dynamic substrate that transduces a biological activity into an electrical signal has been developed (see scheme). The enzymatic conversion of a redox-inactive substrate presented at a self-assembled monolayer produced a redox-active product that is monitored electrochemically in real time.

Original languageEnglish (US)
Pages (from-to)3121-3124
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number27
StatePublished - Jul 14 2003


  • Cyclic voltammetry
  • Enzymes
  • Interfaces
  • Redox chemistry
  • Self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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