TY - JOUR
T1 - Self-rated health among women with coronary disease
T2 - Depression is as important as recent cardiovascular events
AU - Ruo, Bernice
AU - Bertenthal, Daniel
AU - Sen, Saunak
AU - Bittner, Vera
AU - Ireland, Christine C.
AU - Hlatky, Mark A.
N1 - Funding Information:
The HERS trial was funded by a grant from Wyeth-Ayerst Research. Daniel Bertenthal and Saunak Sen were supported by the Health Services Research Enhancement Award Program (REAP) at the San Francisco Veteran Affairs Medical Center. The study design, data analyses, interpretation of the results, or manuscript preparation was not influenced by the sponsoring entity. The authors have no conflicts of interest to disclose.
PY - 2006/11
Y1 - 2006/11
N2 - Background: Prior studies have shown an association between depression and self-rated health among patients with coronary disease. However, the magnitude of the effect of depression on self-rated health compared with that of major clinical events is unknown. Our main objective was to clarify the association between depression and self-rated health using longitudinal data. Methods: We performed a prospective cohort study of 2675 postmenopausal women with coronary disease. The primary predictor variable was a 4-state categorical depression variable based on the Burnam depression screen assessed at sequential visits. The outcome variable was self-rated overall health (excellent, very good, or good vs fair or poor). Results: After adjustment for age, comorbidities, prior self-rated health, and interim events, women with depression at both current and prior annual visits had a >5-fold increased odds of fair/poor self-rated health (odds ratio [OR] 5.1, 95% CI 3.8-6.8). New depression was associated with a >2-fold increased odds of fair/poor self-rated health (OR 2.6, 95% CI 2.0-3.4). Having a history of depression at the preceding annual visit but not at the current visit was associated with a slight increased odds of fair/poor self-rated health (OR 1.3, 95% CI 1.0-1.7). The magnitude of the impact of persistent or new depression was comparable to that of recent angina, myocardial infarction, angioplasty, heart failure, or bypass surgery. Conclusions: Women with persistent or new depression are more likely to report fair/poor self-rated health. The magnitude of the impact of persistent or new depression is comparable to that of major cardiac events.
AB - Background: Prior studies have shown an association between depression and self-rated health among patients with coronary disease. However, the magnitude of the effect of depression on self-rated health compared with that of major clinical events is unknown. Our main objective was to clarify the association between depression and self-rated health using longitudinal data. Methods: We performed a prospective cohort study of 2675 postmenopausal women with coronary disease. The primary predictor variable was a 4-state categorical depression variable based on the Burnam depression screen assessed at sequential visits. The outcome variable was self-rated overall health (excellent, very good, or good vs fair or poor). Results: After adjustment for age, comorbidities, prior self-rated health, and interim events, women with depression at both current and prior annual visits had a >5-fold increased odds of fair/poor self-rated health (odds ratio [OR] 5.1, 95% CI 3.8-6.8). New depression was associated with a >2-fold increased odds of fair/poor self-rated health (OR 2.6, 95% CI 2.0-3.4). Having a history of depression at the preceding annual visit but not at the current visit was associated with a slight increased odds of fair/poor self-rated health (OR 1.3, 95% CI 1.0-1.7). The magnitude of the impact of persistent or new depression was comparable to that of recent angina, myocardial infarction, angioplasty, heart failure, or bypass surgery. Conclusions: Women with persistent or new depression are more likely to report fair/poor self-rated health. The magnitude of the impact of persistent or new depression is comparable to that of major cardiac events.
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U2 - 10.1016/j.ahj.2006.01.012
DO - 10.1016/j.ahj.2006.01.012
M3 - Article
C2 - 17070159
AN - SCOPUS:33750299500
SN - 0002-8703
VL - 152
SP - 921.e1-921.e7
JO - American Heart Journal
JF - American Heart Journal
IS - 5
ER -