TY - JOUR
T1 - Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study
AU - Callahan, Kathryn E.
AU - Lovato, Laura
AU - Miller, Michael E.
AU - Marsh, Anthony P.
AU - Fielding, Roger A.
AU - Gill, Thomas M.
AU - Groessl, Erik J.
AU - Guralnik, Jack
AU - King, Abby C.
AU - Kritchevsky, Stephen B.
AU - McDermott, Mary M.
AU - Manini, Todd
AU - Newman, Anne B.
AU - Rejeski, W. Jack
N1 - Funding Information:
Financial Disclosure: The LIFE Study is funded by National Institutes of Health (NIH), National Institute on Aging (NIA) Cooperative Agreement U01 AG22376 and a supplement from the National Heart, Lung, and Blood Institute (3U01AG022376–05A2S) and sponsored in part by the Intramural Research Program, NIA, NIH. The research is partially supported by the Claude D. Pepper Older Americans Independence Centers at the University of Florida (1 P30 AG028740), Wake Forest University (P30 AG21332), Tufts University (1P30AG031679), University of Pittsburgh (P30 AG024827), and Yale University (P30AG021342) and the NIH, National Center for Research Resources Clinical and Translational Science Awards at Stanford University (UL1 RR025744). Tufts University is also supported by the Boston Rehabilitation Outcomes Center (1R24HD065688–01A1).
Funding Information:
Dr. Callahan’s work was supported by the Wake Forest University Claude D. Pepper Older Americans Independence Center (OAIC) (P30-AG21332). Dr. Gill is the recipient of an Academic Leadership Award (K07AG043587) from the NIA and Yale OAIC. Dr. Fielding (Tufts University) is partially supported by the U.S. Department of Agriculture under Agreement 58–1950–0-014. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the view of the NIH, NIA, or U.S. Department of Agriculture.
PY - 2018/10
Y1 - 2018/10
N2 - Objectives: To explore whether baseline scores on the Mobility Assessment Tool—short form (MAT-sf), a brief, animated, computer-based means of assessing mobility that predicts mobility disability, are associated with number of hospitalizations and time to first hospitalization over a median follow-up of 2.7 years. Design: Post hoc analysis of prospectively gathered data from the Lifestyle Interventions and Independence for Elders (LIFE) Study, a randomized clinical trial of lifestyle interventions to preserve mobility in older adults. Setting: Eight U.S. academic medical centers. Participants: Of 1,635 sedentary community-dwelling older adults enrolled in LIFE, 1,574 completed baseline physical function screening including the MAT-sf, with baseline scores ranging from 30.2 (low function) to 69.8 (high function) on a scale from 30 to 80. Measurements: Number of hospitalizations and time to first hospitalization, adjusted for age, sex, race, living alone, clinical site, baseline comorbidities, number of prescription medications, and cognition. Results: Of the 1,557 participants with data regarding hospitalization status, 726 (47%) had at least 1 hospitalization; 78% of these had 1 or 2 hospitalizations. For every 10-point lower MAT-sf score, the rate of all hospitalizations was 19% higher in those with lower scores (adjusted rate ratio=1.20, 95% confidence interval (CI)=1.08–1.32, p<.001). Lower baseline MAT-sf scores were also associated with greater risk of first hospitalization (adjusted hazard ratio=1.20, 95% CI=1.09–1.32, p<.01, per 10-point lower MAT-sf score). Conclusion: Low MAT-sf scores identify older adults at risk of hospitalization; further study is needed to test interventions to reduce hospitalizations in these individuals.
AB - Objectives: To explore whether baseline scores on the Mobility Assessment Tool—short form (MAT-sf), a brief, animated, computer-based means of assessing mobility that predicts mobility disability, are associated with number of hospitalizations and time to first hospitalization over a median follow-up of 2.7 years. Design: Post hoc analysis of prospectively gathered data from the Lifestyle Interventions and Independence for Elders (LIFE) Study, a randomized clinical trial of lifestyle interventions to preserve mobility in older adults. Setting: Eight U.S. academic medical centers. Participants: Of 1,635 sedentary community-dwelling older adults enrolled in LIFE, 1,574 completed baseline physical function screening including the MAT-sf, with baseline scores ranging from 30.2 (low function) to 69.8 (high function) on a scale from 30 to 80. Measurements: Number of hospitalizations and time to first hospitalization, adjusted for age, sex, race, living alone, clinical site, baseline comorbidities, number of prescription medications, and cognition. Results: Of the 1,557 participants with data regarding hospitalization status, 726 (47%) had at least 1 hospitalization; 78% of these had 1 or 2 hospitalizations. For every 10-point lower MAT-sf score, the rate of all hospitalizations was 19% higher in those with lower scores (adjusted rate ratio=1.20, 95% confidence interval (CI)=1.08–1.32, p<.001). Lower baseline MAT-sf scores were also associated with greater risk of first hospitalization (adjusted hazard ratio=1.20, 95% CI=1.09–1.32, p<.01, per 10-point lower MAT-sf score). Conclusion: Low MAT-sf scores identify older adults at risk of hospitalization; further study is needed to test interventions to reduce hospitalizations in these individuals.
KW - hospitalization
KW - mobility
KW - physical function
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U2 - 10.1111/jgs.15468
DO - 10.1111/jgs.15468
M3 - Article
C2 - 30281796
AN - SCOPUS:85054419155
VL - 66
SP - 1927
EP - 1933
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
SN - 0002-8614
IS - 10
ER -