SELF-STARVATION OF RATS LIVING IN ACTIVITY WHEELS ON A RESTRICTED FEEDING SCHEDULE

ARYEH ROUTTENBERG*, ABBY W. KUZNESOF

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

313 Scopus citations

Abstract

SS MAINTAINED ON 23-HR FOOD DEPRIVATION CYCLES WERE HOUSED IN ACTIVITY WHEELS (EXPERIMENTAL) OR STANDARD LABORATORY CAGES (CONTROL). EXPERIMENTAL SS WERE UNABLE TO MAINTAIN BODY WEIGHT AND DIET; DESPITE HIGH LEVELS OF ACTIVITY, EXPERIMENTAL SS ATE SIGNIFICANTLY LESS THAN CONTROLS. INTERPOSING A 3-HR PERIOD BETWEEN RUNNING AND FEEDING, ADAPTING SS TO AREA OF FEEDING, OR ADMINISTERING PENTOBARBITAL (4 MG/KG) HAD LITTLE INFLUENCE ON THIS FOOD-INTAKE REDUCTION ("SELF-STARVATION"). CHLORPROMAZINE ADMINISTRATION (1 MG/KG) REDUCED ACTIVITY AND DID HAVE A SIGNIFICANT EFFECT ON SELF-STARVATION. HYPOTHALAMIC INVOLVEMENT IS DISCUSSED IN RELATION TO THERMO- AND GLUCOSTATIC THEORIES OF FEEDING AND A GENERAL EXCITABILITY FACTOR. (26 REF.) (PsycINFO Database Record (c) 2006 APA, all rights reserved).

Original languageEnglish (US)
Pages (from-to)414-421
Number of pages8
JournalJournal of Comparative and Physiological Psychology
Volume64
Issue number3
DOIs
StatePublished - Dec 1 1967

Keywords

  • CHLORPROMAZINE
  • SELF-STARVATION, RESTRICTED FEEDING IN ACTIVITY WHEEL, PENTOBARBITAL &

ASJC Scopus subject areas

  • Medicine(all)

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