Sensitivity volume as figure-of-merit for maximizing data importance in electrical impedance tomography

Claire C. Onsager, Chulin Wang, Charles Costakis, Can C. Aygen, Lauren Lang, Suzan van der Lee, Matthew A. Grayson

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Objective. Electrical impedance tomography (EIT) is a noninvasive imaging method whereby electrical measurements on the periphery of a heterogeneous conductor are inverted to map its internal conductivity. The EIT method proposed here aims to improve computational speed and noise tolerance by introducing sensitivity volume as a figure-of-merit for comparing EIT measurement protocols. Approach. Each measurement is shown to correspond to a sensitivity vector in model space, such that the set of measurements, in turn, corresponds to a set of vectors that subtend a sensitivity volume in model space. A maximal sensitivity volume identifies the measurement protocol with the greatest sensitivity and greatest mutual orthogonality. A distinguishability criterion is generalized to quantify the increased noise tolerance of high sensitivity measurements. Main result. The sensitivity volume method allows the model space dimension to be minimized to match that of the data space, and the data importance to be increased within an expanded space of measurements defined by an increased number of contacts. Significance. The reduction in model space dimension is shown to increase computational efficiency, accelerating tomographic inversion by several orders of magnitude, while the enhanced sensitivity tolerates higher noise levels up to several orders of magnitude larger than standard methods.

Original languageEnglish (US)
Article number045004
JournalPhysiological Measurement
Volume45
Issue number4
DOIs
StatePublished - Apr 1 2024

Funding

This work was supported in part by Northwestern University and NSF grants ECCS-1912694, DMR-1720139, and support from Leslie and Mac McQuown.

Keywords

  • computational efficiency
  • data importance
  • distinguishability
  • electrical impedance tomography
  • inverse problem
  • noise tolerance
  • sensitivity volume

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Biomedical Engineering
  • Physiology (medical)

Fingerprint

Dive into the research topics of 'Sensitivity volume as figure-of-merit for maximizing data importance in electrical impedance tomography'. Together they form a unique fingerprint.

Cite this