Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice

Yingyue Xu, Mary Ann Cheatham, Jonathan H Siegel

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Descending neural pathways in the mammalian auditory system are believed to modulate the function of the peripheral auditory system [3, 8, 10]. These pathways include the medial olivocochlear (MOC) efferent innervation to the cochlear outer hair cells (OHCs) and the acoustic reflex pathways mediating middle ear muscle (MEM) contractions. The MOC effects can be monitored noninvasively using otoacoustic emissions (OAEs) [5, 6], which are acoustic byproducts of cochlear function [7]. In this study, we applied a sensitive method to determine when and to what degree contralateral MEM suppression contaminated MOC efferent effects on TEOAEs in unanesthetized mice. The lowest contralateral broadband noise evoking MEM contractions varied across animals. Examples of potential MOC-mediated TEOAE suppression with contralateral noise below MEM contraction thresholds were seen, but this behavior did not occur in the majority of cases.

Original languageEnglish (US)
Title of host publicationMechanics of Hearing
Subtitle of host publicationProtein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing
EditorsDavid P. Corey, K. Domenica Karavitaki
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735413504
DOIs
StatePublished - Dec 31 2015
Event12th International Workshop on the Mechanics of Hearing: Protein to Perception - Cape Sounio, Greece
Duration: Jun 23 2014Jun 29 2014

Publication series

NameAIP Conference Proceedings
Volume1703
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other12th International Workshop on the Mechanics of Hearing: Protein to Perception
CountryGreece
CityCape Sounio
Period6/23/146/29/14

Fingerprint

middle ear
reflexes
muscular function
mice
acoustics
retarding
hair
muscles
animals
broadband
thresholds

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science
  • Physics and Astronomy(all)
  • Nature and Landscape Conservation

Cite this

Xu, Y., Cheatham, M. A., & Siegel, J. H. (2015). Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice. In D. P. Corey, & K. D. Karavitaki (Eds.), Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing [090026] (AIP Conference Proceedings; Vol. 1703). American Institute of Physics Inc.. https://doi.org/10.1063/1.4939424
Xu, Yingyue ; Cheatham, Mary Ann ; Siegel, Jonathan H. / Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice. Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. editor / David P. Corey ; K. Domenica Karavitaki. American Institute of Physics Inc., 2015. (AIP Conference Proceedings).
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Xu, Y, Cheatham, MA & Siegel, JH 2015, Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice. in DP Corey & KD Karavitaki (eds), Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing., 090026, AIP Conference Proceedings, vol. 1703, American Institute of Physics Inc., 12th International Workshop on the Mechanics of Hearing: Protein to Perception, Cape Sounio, Greece, 6/23/14. https://doi.org/10.1063/1.4939424

Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice. / Xu, Yingyue; Cheatham, Mary Ann; Siegel, Jonathan H.

Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. ed. / David P. Corey; K. Domenica Karavitaki. American Institute of Physics Inc., 2015. 090026 (AIP Conference Proceedings; Vol. 1703).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Xu Y, Cheatham MA, Siegel JH. Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice. In Corey DP, Karavitaki KD, editors, Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. American Institute of Physics Inc. 2015. 090026. (AIP Conference Proceedings). https://doi.org/10.1063/1.4939424