Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation

Joseph Kapelushnik*, Dan Engelhard, Jayesh Mehta, Reuven Or, Yuval Brandstetter, Elie Picard, Gabriel Cividalli, Arnon Nagler

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

A 6‐month‐old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV‐ and CMV‐induced lung injury in these life‐threatening infections. © 1995 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)169-171
Number of pages3
JournalJournal of Medical Virology
Volume46
Issue number2
DOIs
StatePublished - Jan 1 1995

Keywords

  • bone marrow transplantation
  • cytomegalovirus
  • familial hemophagocytic lymphohistiocytosis
  • interstitial pneumonia
  • respiratory syncytial virus

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

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    Kapelushnik, J., Engelhard, D., Mehta, J., Or, R., Brandstetter, Y., Picard, E., Cividalli, G., & Nagler, A. (1995). Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation. Journal of Medical Virology, 46(2), 169-171. https://doi.org/10.1002/jmv.1890460216