Serial electrodiagnostic studies in West Nile virus - Associated acute flaccid paralysis

Christina Marciniak*, Evan L. Rosenfeld

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A man in his 70s presented for acute rehabilitation with severe acute flaccid asymmetric weakness in both lower limbs. Cerebrospinal fluid and serum immunoglobulin M titers were positive for West Nile virus. Electrodiagnostic studies demonstrated severe diffuse motor axonopathy consistent with an anterior myelitis. Electrodiagnostic and clinical improvements were monitored. Electrodiagnostic testing at 6 and 18 mos demonstrated continuing reinnervation; nascent voluntary motor unit action potentials were first noted proximally and, at 18 mos, distally in the left lower limb, including muscles in which motor unit potentials were not initially noted. Corresponding clinical improvements, though slow, were demonstrated even at 1 1/2 yrs after onset. Thus, motoric changes after West Nile virus-associated anterior myelitis need to be monitored over a prolonged time period to allow accurate assessment of prognosis for recovery in rehabilitation programs.

Original languageEnglish (US)
Pages (from-to)904-910
Number of pages7
JournalAmerican Journal of Physical Medicine and Rehabilitation
Issue number11
StatePublished - Nov 2005


  • Anterior Myelitis
  • Electrodiagnosis
  • Rehabilitation
  • West Nile virus

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation


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