Serum antibodies to HTLV‐I in human demyelinating disease

L. Epstein; B. Blumberg; J. Crowley; K. Samuel; J. Goudsmit; S. Cook; P. Dowling

doi:10.1111/j.1600-0404.1987.tb07925.x

Serum antibodies to HTLV‐I in human demyelinating disease

L. Epstein^*, B. Blumberg, J. Crowley, K. Samuel, J. Goudsmit, S. Cook, P. Dowling

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

Original language	English (US)
Pages (from-to)	231-233
Number of pages	3
Journal	Acta Neurologica Scandinavica
Volume	75
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0404.1987.tb07925.x
State	Published - Apr 1987

Keywords

Guillain‐Barre syndrome
HTLV‐I
multiple sclerosis

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1111/j.1600-0404.1987.tb07925.x

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abstract = "ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barr{\'e} Syndrome (GBS) patients was found.",

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author = "L. Epstein and B. Blumberg and J. Crowley and K. Samuel and J. Goudsmit and S. Cook and P. Dowling",

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AU - Epstein, L.

AU - Blumberg, B.

AU - Crowley, J.

AU - Samuel, K.

AU - Goudsmit, J.

AU - Cook, S.

AU - Dowling, P.

PY - 1987/4

Y1 - 1987/4

N2 - ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

AB - ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

KW - Guillain‐Barre syndrome

KW - HTLV‐I

KW - multiple sclerosis

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Serum antibodies to HTLV‐I in human demyelinating disease

Abstract

Keywords

ASJC Scopus subject areas

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