Serum antibodies to HTLV‐I in human demyelinating disease

L. Epstein*, B. Blumberg, J. Crowley, K. Samuel, J. Goudsmit, S. Cook, P. Dowling

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

Original languageEnglish (US)
Pages (from-to)231-233
Number of pages3
JournalActa Neurologica Scandinavica
Volume75
Issue number4
DOIs
StatePublished - Apr 1987

Keywords

  • Guillain‐Barre syndrome
  • HTLV‐I
  • multiple sclerosis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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