Serum antibodies to HTLV‐I in human demyelinating disease

L. Epstein; B. Blumberg; J. Crowley; K. Samuel; J. Goudsmit; S. Cook; P. Dowling

doi:10.1111/j.1600-0404.1987.tb07925.x

Serum antibodies to HTLV‐I in human demyelinating disease

L. Epstein^*, B. Blumberg, J. Crowley, K. Samuel, J. Goudsmit, S. Cook, P. Dowling

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

Original language	English (US)
Pages (from-to)	231-233
Number of pages	3
Journal	Acta Neurologica Scandinavica
Volume	75
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0404.1987.tb07925.x
State	Published - Apr 1987

Keywords

Guillain‐Barre syndrome
HTLV‐I
multiple sclerosis

ASJC Scopus subject areas

Neurology
Clinical Neurology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1600-0404.1987.tb07925.x

Cite this

@article{516a1480fa8944af94df0c2d25ce420f,

title = "Serum antibodies to HTLV‐I in human demyelinating disease",

abstract = "ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barr{\'e} Syndrome (GBS) patients was found.",

keywords = "Guillain‐Barre syndrome, HTLV‐I, multiple sclerosis",

author = "L. Epstein and B. Blumberg and J. Crowley and K. Samuel and J. Goudsmit and S. Cook and P. Dowling",

year = "1987",

month = apr,

doi = "10.1111/j.1600-0404.1987.tb07925.x",

language = "English (US)",

volume = "75",

pages = "231--233",

journal = "Acta Neurologica Scandinavica",

issn = "0001-6314",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - Serum antibodies to HTLV‐I in human demyelinating disease

AU - Epstein, L.

AU - Blumberg, B.

AU - Crowley, J.

AU - Samuel, K.

AU - Goudsmit, J.

AU - Cook, S.

AU - Dowling, P.

PY - 1987/4

Y1 - 1987/4

N2 - ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

AB - ABSTRACT— Serum HTLV‐I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV‐I core protein antigens and an immunoblot assay with E. coli‐expressed P21E transmembrane protein was employed to detect antibodies to HTLV‐I evelope antigens. No serologic evidence of prior HTLV‐I infection in our population of multiple sclerosis (MS) or Guillain‐Barré Syndrome (GBS) patients was found.

KW - Guillain‐Barre syndrome

KW - HTLV‐I

KW - multiple sclerosis

UR - http://www.scopus.com/inward/record.url?scp=0023254237&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023254237&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0404.1987.tb07925.x

DO - 10.1111/j.1600-0404.1987.tb07925.x

M3 - Article

C2 - 2884798

AN - SCOPUS:0023254237

SN - 0001-6314

VL - 75

SP - 231

EP - 233

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

IS - 4

ER -

Serum antibodies to HTLV‐I in human demyelinating disease

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this