@article{6767b1e2a8bb4b27856416a1f607fcb1,
title = "Serum creatine phosphokinase and aldolase activity in acute schizophrenic patients and their relatives",
abstract = "Increased activity of cieatine phosphokinase (CPK) or aldolase, or both, was found, on a blind basis, in the serum of 25 of 39 acute schizophrenic patients at some phase of their illness. The median increase in serum enzyme activity was approximately threefold. Smaller increases in serum CPK and aldolase activity were also found in five of 22 first-degree relatives of the acute patients. In the patients, the serum enzyme activity increased briefly and returned to normal but the enzyme increases were persistent in the relatives.",
author = "Meltzer, {Herbert Y.} and Lester Grinspoon and Shader, {Richard I.}",
note = "Funding Information: From the Department of Psychiatry, University of Chicago Pritzker School of Medicine and the Massachusetts Mental Health Center, Boston, Mass. Supported in part by USPHS Grants 5-POI-MH-12556-02 and MH-16127-01 and State o] Illinois Grant 17-340. H~EaT Y. MELTZER, M.A., M.D.: Assistant Pro[essor of Psychiatry, Department of Psychiatry, University of Chicago Pritzker School of Medicine; Consultant, Illinois State Psychiatric Institute, Chicago, Ill. LESTER G~INSPOO~, M.D.: Associate Professor of Psychiatry, Harvard University School of Medicine; Director of Research, Massachusetts Mental Health Center, Boston, Mass. RICHARD I. SI~ADER, M.D.: Assistant Professor o~ Psychiatry, Harvard University School of Medicine; Assistant Clinical Director, Massachusetts Mental Health Center, Boston, Mass.",
year = "1970",
month = nov,
doi = "10.1016/0010-440X(70)90018-0",
language = "English (US)",
volume = "11",
pages = "552--558",
journal = "Comprehensive Psychiatry",
issn = "0010-440X",
publisher = "W.B. Saunders Ltd",
number = "6",
}
