Severe pandemic (H1N1) 2009 influenza with false negative direct fluorescent antibody assay: Case series

Luciano Kapelusznik; Rupa Patel; Jennifer Jao; Gopi Patel; Simon Daefler; Vincent LaBombardi; David Calfee

doi:10.1016/j.jcv.2009.07.023

Severe pandemic (H1N1) 2009 influenza with false negative direct fluorescent antibody assay: Case series

Luciano Kapelusznik^*, Rupa Patel, Jennifer Jao, Gopi Patel, Simon Daefler, Vincent LaBombardi, David Calfee

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Between May and June of 2009 we observed 4 patients that presented with severe influenza-like symptoms and respiratory failure. All cases tested negative for influenza A and B by direct fluorescent antibody assay. Further investigation revealed all cases to be positive for pandemic (H1N1) 2009 influenza virus by real-time RT-PCR. This article includes a description of these cases and the characteristics associated with them.

Original language	English (US)
Pages (from-to)	279-281
Number of pages	3
Journal	Journal of Clinical Virology
Volume	46
Issue number	3
DOIs	https://doi.org/10.1016/j.jcv.2009.07.023
State	Published - Nov 1 2009

Keywords

DFA
H1N1
Pandemic H1N1 influenza
Respiratory failure
S-OIV
Swine influenza

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.1016/j.jcv.2009.07.023

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Cite this

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title = "Severe pandemic (H1N1) 2009 influenza with false negative direct fluorescent antibody assay: Case series",

abstract = "Between May and June of 2009 we observed 4 patients that presented with severe influenza-like symptoms and respiratory failure. All cases tested negative for influenza A and B by direct fluorescent antibody assay. Further investigation revealed all cases to be positive for pandemic (H1N1) 2009 influenza virus by real-time RT-PCR. This article includes a description of these cases and the characteristics associated with them.",

keywords = "DFA, H1N1, Pandemic H1N1 influenza, Respiratory failure, S-OIV, Swine influenza",

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AU - Kapelusznik, Luciano

AU - Patel, Rupa

AU - Jao, Jennifer

AU - Patel, Gopi

AU - Daefler, Simon

AU - LaBombardi, Vincent

AU - Calfee, David

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KW - DFA

KW - H1N1

KW - Pandemic H1N1 influenza

KW - Respiratory failure

KW - S-OIV

KW - Swine influenza

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