Severe Pseudomonas aeruginosa infections: Tackling the conundrum of drug resistance

Alan R Hauser*, Padman Sriram

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


Pseudomonas aeruginosa infections are a frequent cause of morbidity and mortality in hospitalized patients. Treatment of these infections is complicated by the intrinsic and acquired resistance of this bacterium to many commonly used antimicrobial agents. In this article, Drs Hauser and Sriram argue that careful consideration of the mechanisms by which P aeruginosa resists the activity of antimicrobial agents is essential for optimal treatment decisions. Although many aspects of treatment of severe P aeruginosa infections remain controversial, the authors suggest specific treatment options for patients both before and after susceptibilities are known.

Original languageEnglish (US)
Pages (from-to)41-48
Number of pages8
JournalPostgraduate Medicine
Issue number1
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Medicine(all)


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