Abstract
Topiramate has recently been reported to cause hyperthermia as a result of oligohydrosis, primarily in pediatric patients. All cases reported to date were clinically mild, without permanent systemic or neurologic dysfunction. We report a case of severe hyperthermia and subsequent ataxia and tremor in an adult treated with topiramate. To our knowledge, this is the first case of topiramate-associated hyperthermia to result in residual cerebellar and cognitive dysfunction.
Original language | English (US) |
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Pages (from-to) | 94-95 |
Number of pages | 2 |
Journal | Clinical neuropharmacology |
Volume | 28 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2005 |
Keywords
- Cerebellar dysfunction
- Hyperthermia
- Topiramate
ASJC Scopus subject areas
- Clinical Neurology
- Pharmacology (medical)
- Pharmacology