Sex and race differences in sodium-litiihjm countertransport and red cell sodium concentration

Maurizio Trevisan, David Ostrow, Richard S. Cooper, Christopher Sempos, Jeremiah Stamler*

*Corresponding author for this work

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

A total of 417 Individuals from all four major sex-race groups were examined for the rate of sodium flux via the countertransport pathway and the sodium concentration within red cells. The age span was from early adolescence to retirement. Males of both races had sizably higher countertransport rates than did women (p < 0.01), and a slight increase in sodium concentration (p > 0.05). Contrariwise, white whites of both sexes had higher countertransport than their black counterparts, sodium concentration was higher in blacks than whites (p < 0.01). This pattern is not consistent with a direct relationship between both countertransport or sodium concentratIon and blood pressure which ap plies across both racial groups. Sex-race differences must be taken into ac count in any group comparisons of these variables.

Original languageEnglish (US)
Pages (from-to)537-541
Number of pages5
JournalAmerican journal of epidemiology
Volume120
Issue number4
DOIs
StatePublished - Oct 1984

Keywords

  • Biological transport
  • Blacks
  • Hypertension
  • Lithium
  • Sex
  • Sodium
  • Whites

ASJC Scopus subject areas

  • Epidemiology

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